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DNA damage response drugs for cancer yield continued synthetic lethality learnings
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date : 2022-05-17 , DOI: 10.1038/d41573-022-00092-4
Asher Mullard

A PARP1-selective drug and a pipeline of ATR inhibitors demonstrate the near-term opportunities and long-term challenges for synthetic lethality in anticancer drug development.

中文翻译:

用于癌症的 DNA 损伤反应药物产生持续的合成杀伤力学习

一种 PARP1 选择性药物和一系列 ATR 抑制剂证明了合成杀伤力在抗癌药物开发中的近期机遇和长期挑战。
更新日期:2022-05-17
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