Protein arginine methyltransferases (PRMTs) are overexpressed in many cancer types, including triple-negative breast cancer (TNBC). A new study shows that a reversible inhibitor of type I PRMTs suppresses TNBC tumor growth by inducing a viral mimicry response with retained introns.

中文翻译：

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将内含子放在保持器上

蛋白质精氨酸甲基转移酶 (PRMT) 在许多癌症类型中过度表达，包括三阴性乳腺癌 (TNBC)。一项新研究表明，I 型 PRMT 的可逆抑制剂通过诱导保留内含子的病毒模拟反应来抑制 TNBC 肿瘤生长。