An 8-week feeding trial was carried out to explore the effects of fish meal replacement with low-gossypol cottonseed meal, a potential alternative protein source, in juvenile turbot (Scophthalmus maximus L.). Five isonitrogenous and isoenergetic diets, with different substitutional levels (0%, 15%, 25%, 35% and 45%, respectively), were formulated. The growth performance, feed utilization and haematological responses were determined. Compared with the fishmeal group, fish growth was not affected when the replacement level was no more than 35%. The feed efficiency ratio and protein efficiency ratio in LC45 group were significantly lower. The apparent digestibility coefficients (ADCs) of dry matter and crude protein, as well as the ADCs of lysine and proline, were inhibited when the replacement level reached 25%. Furthermore, the glucose and cholesterol levels in plasma in LC45 group were significantly lower than that in FM group. Significantly lower content of malondialdehyde was observed in LC25 group while the activities of alanine aminotransferase and aspartate aminotransferase in LC45 were significantly induced. The height of intestinal villi in LC45 was significantly lower than in other groups. Overall, the results indicate that low-gossypol cottonseed meal could be used as an alternative plant protein source in turbot and it could replace 35% fishmeal in the diet.

进行了为期 8 周的喂养试验，以探索用低棉酚棉籽粉替代鱼粉对幼鱼（Scophthalmus maximus ）的影响，该棉籽粉是一种潜在的替代蛋白质来源。L.)。制定了五种具有不同替代水平（分别为 0%、15%、25%、35% 和 45%）的等氮和等能饮食。测定生长性能、饲料利用率和血液学反应。与鱼粉组相比，当更换水平不超过35%时，鱼类生长不受影响。LC45组的饲料效率比和蛋白质效率比显着降低。当替代水平达到25%时，干物质和粗蛋白的表观消化系数（ADCs）以及赖氨酸和脯氨酸的ADCs受到抑制。此外，LC45组血浆中的葡萄糖和胆固醇水平显着低于FM组。LC25组丙二醛含量显着降低，而LC45组丙氨酸氨基转移酶和天冬氨酸氨基转移酶活性显着诱导。LC45组肠绒毛高度明显低于其他组。总体而言，结果表明，低棉酚棉籽粕可用作大菱鲆的替代植物蛋白来源，可替代日粮中 35% 的鱼粉。