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Can maternal-child microbial seeding interventions improve the health of infants delivered by Cesarean section?
Cell Host & Microbe ( IF 30.3 ) Pub Date : 2022-05-11 , DOI: 10.1016/j.chom.2022.02.014 Suchitra K Hourigan 1 , Maria Gloria Dominguez-Bello 2 , Noel T Mueller 3
中文翻译:
母婴微生物接种干预能否改善剖宫产婴儿的健康?
更新日期:2022-05-12
Cell Host & Microbe ( IF 30.3 ) Pub Date : 2022-05-11 , DOI: 10.1016/j.chom.2022.02.014 Suchitra K Hourigan 1 , Maria Gloria Dominguez-Bello 2 , Noel T Mueller 3
Affiliation
Maternal-child microbial seeding interventions expose Cesarean-section (C-section)-delivered infants to the maternal microbiome they bypass during Cesarean delivery. It is theorized such interventions restore the microbiome and normalize immune development to reduce the occurrence of C-section-associated inflammatory conditions. Here we discuss the rationale, evidence, and controversies surrounding such interventions.
中文翻译:
母婴微生物接种干预能否改善剖宫产婴儿的健康?
母婴微生物接种干预措施使剖宫产(C-section)分娩的婴儿接触到他们在剖宫产期间绕过的母体微生物组。从理论上讲,此类干预措施可恢复微生物组并使免疫发育正常化,以减少剖腹产相关炎症的发生。在这里,我们讨论了围绕此类干预措施的基本原理、证据和争议。