In the present study, a selective and sensitive electrochemical sensor based on molecular imprinted polymer (MIP) for p-nitrophenol (p-NP) detection was developed. For this purpose, MIP was synthesized by precipitation polymerization using methacrylic acid as a functional monomer, ethylene glycol diacrylate as a crosslinking monomer. The morphology and thermal stability were studied using SEM (scanning electron microscopy) and TGA (thermogravimetric analysis) along with FTIR (Fourier-transform infrared) analysis. The electroreduction of p-NP was studied on modified electrode using cyclic voltammetry and diffusion amperometry with LOD (limit of detection) and LOQ (Limit of quantitation) were 0.2 µM and 0.7 µM, respectively, which showed a linear response in a 2 × 10⁻⁶ M to 4 × 10⁻⁴ M concentration range. The process parameters (coating volume, pH, exposure time) also affected the efficiency of p-NP detection. The fabricated sensor was employed to monitor and detect p-NP in real wastewater sample and up to 95–96% recovery was achieved. Hence, the developed MIP based sensor could be employed for the monitoring and p-NP detection in the effluents.

在本研究中，开发了一种基于分子印迹聚合物（MIP）的选择性和灵敏的电化学传感器，用于检测对硝基苯酚（p-NP）。为此，使用甲基丙烯酸作为功能单体，乙二醇二丙烯酸酯作为交联单体，通过沉淀聚合合成MIP。使用 SEM（扫描电子显微镜）和 TGA（热重分析）以及 FTIR（傅里叶变换红外）分析研究了形态和热稳定性。使用循环伏安法和扩散电流法在修饰电极上研究 p-NP 的电还原，LOD（检测限）和 LOQ（定量限）分别为 0.2 µM 和 0.7 µM，在 2 × 10 ^-6 M 至 4 × 10 ^-4M 浓度范围。工艺参数（涂层体积、pH、曝光时间）也影响 p-NP 检测的效率。制造的传感器用于监测和检测实际废水样品中的 p-NP，回收率高达 95-96%。因此，开发的基于 MIP 的传感器可用于监测和检测流出物中的 p-NP。