Eosinophilic/T-cell chorionic vasculitis was initially defined as “a new form of chorionic vasculitis characterized by an infiltrate composed primarily of eosinophils and CD3⁺ T lymphocytes ... [that] occurs in the absence of any evidence of chorioamnionitis.” No subsequent reports have directly addressed whether histologic evidence suggestive of amniotic fluid infection should preclude its diagnosis. The case reported here describes a term placenta with mild acute chorionitis, moderate acute subchorionitis, mild acute chorionic vasculitis, and funisitis associated with multifocal eosinophilic/T-cell chorionic vasculitis. It shows unequivocally, with immunohistochemical staining, that eosinophilic/T-cell chorionic vasculitis and acute chorionic vasculitis can be seen and histologically distinguished in the same case. The paper shows how differing interpretations of inclusion and exclusion criteria by investigators have affected estimates of the incidence of this rare lesion. There is a need to harmonize diagnostic criteria; the report describes how cases with both entities can be documented carefully.

嗜酸性粒细胞/T细胞绒毛膜血管炎最初被定义为“一种新形式的绒毛膜血管炎，其特征是浸润主要由嗜酸性粒细胞和CD3 ⁺T 淋巴细胞……在没有任何绒毛膜羊膜炎证据的情况下发生。” 没有后续报告直接说明提示羊水感染的组织学证据是否应排除其诊断。本文报道的病例描述了一个术语胎盘伴轻度急性绒毛膜炎、中度急性绒毛膜下炎、轻度急性绒毛膜血管炎和与多灶性嗜酸性粒细胞/T 细胞绒毛膜血管炎相关的滑膜炎。免疫组化染色明确显示，在同一病例中可以看到嗜酸性/T细胞绒毛膜血管炎和急性绒毛膜血管炎，并在组织学上加以区分。该论文展示了研究人员对纳入和排除标准的不同解释如何影响对这种罕见病变发生率的估计。需要统一诊断标准；该报告描述了如何仔细记录这两个实体的案件。