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A compact, practical photoreactor for multi-reaction arrays
Reaction Chemistry & Engineering ( IF 3.9 ) Pub Date : 2022-05-06 , DOI: 10.1039/d2re00062h
Gregory D. Brown 1 , Daniel Batalla 1 , Cullen L. Cavallaro 1 , Heidi L. Perez 1 , Stephen T. Wrobleski 1 , Trevor C. Sherwood 1
Affiliation  

The Bristol Myers Squibb Photoreactor (BMS-PR) is a convenient, small-footprint platform that enables routine use of photochemical transformations in a variety of laboratory settings. These photoreactors have been engineered to safely irradiate multiple reaction vessels for array synthesis at various wavelengths and temperatures with a more practical setup than most other commercial photoreactors. The BMS-PR integrates seamlessly with standard laboratory equipment and incorporates a variety of attractive safety features. Herein we describe the BMS-PR460 device for irradiation of reactions at 460 nm using blue light-emitting diodes (LEDs) and highlight its application with photochemical reactions that may be useful in the discovery of novel drug molecules.

中文翻译:

用于多反应阵列的紧凑、实用的光反应器

百时美施贵宝光反应器 (BMS-PR) 是一个方便、占地面积小的平台,可在各种实验室环境中常规使用光化学转化。这些光反应器经过设计,可以安全地照射多个反应容器,以在各种波长和温度下进行阵列合成,其设置比大多数其他商业光反应器更实用。BMS-PR 与标准实验室设备无缝集成,并结合了多种吸引人的安全功能。在这里,我们描述了 BMS-PR460 装置,用于使用蓝色发光二极管 (LED) 在 460 nm 处照射反应,并强调其在光化学反应中的应用,这可能有助于发现新的药物分子。
更新日期:2022-05-06
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