Congenital tuberculosis (CTB) is an uncommon yet, well-defined condition. CTB has a non-specific clinical presentation, making the diagnosis difficult. The rarity of CTB in neonates is due to the difficulty in distinguishing between congenital and postnatally acquired infection, and non-specific symptoms in the newborn, which are often misdiagnosed. Though it has a low incidence, it has significant mortality if the diagnosis is delayed. We are presenting two cases of CTB in newborns who showed signs of disease in the first few days of life. The diagnosis was suspected based on chest computed tomography, magnetic resonance imaging brain, cerebrospinal fluid studies, intrauterine growth restriction, non-response to standard treatment and a maternal history of active tuberculosis. These cases highlight the significance of having a high suspicion of CTB and timely treatment for better outcomes.

中文翻译：

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新生儿播散性先天性结核病：病例系列。

先天性肺结核 (CTB) 是一种罕见但定义明确的疾病。CTB具有非特异性临床表现，使诊断变得困难。新生儿CTB的罕见是由于难以区分先天性和产后获得性感染，以及新生儿的非特异性症状，经常被误诊。虽然发病率低，但如果延误诊断，死亡率很高。我们将介绍两例在出生后几天出现疾病迹象的新生儿 CTB。根据胸部计算机断层扫描、脑部磁共振成像、脑脊液检查、宫内生长受限、对标准治疗无反应和母亲有活动性肺结核病史，怀疑该诊断。