Using the Infant Behavior Questionnaire–Revised in a longitudinal sample of infant siblings of autistic children (HR; n = 427, 171 female, 83.4% White) and a comparison group of low-risk controls (LR, n = 200, 86 female, 81.5% White), collected between 2007 and 2017, this study identified an invariant factor structure of temperament traits across groups at 6 and 12 months. Second, after partitioning the groups by familial risk and diagnostic outcome at 24 months, results reveal an endophenotypic pattern of Positive Emotionality at both 6 and 12 months, (HR-autism spectrum disorder [ASD] < HR-no-ASD < LR). Third, increased ‘Duration of Orienting’ at 12 months was associated with lower scores on the 24-month developmental outcomes in HR infants. These findings may augment efforts for early identification of ASD.

中文翻译：

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检查婴儿行为问卷的因素结构和区分效用——针对自闭症儿童的婴儿兄弟姐妹进行修订

使用婴儿行为问卷——在自闭症儿童的婴儿兄弟姐妹的纵向样本中进行修订（HR；n  = 427，171 名女性，83.4% 白人）和低风险对照对照组（LR，n  = 200，86 名女性， 81.5% 白人），收集于 2007 年至 2017 年间，这项研究确定了 6 个月和 12 个月时各组气质特征的不变因素结构。其次，根据家族风险和 24 个月时的诊断结果对各组进行分组后，结果揭示了 6 个月和 12 个月时积极情绪的内表型模式（HR-自闭症谱系障碍 [ASD] < HR-no-ASD < LR）。第三，HR 婴儿在 12 个月时增加“定向持续时间”与 24 个月发育结果得分较低相关。这些发现可能会增强早期识别 ASD 的努力。