The current study estimates the impact of different common herbicides on antioxidant defenses and histological structure of liver and spinal cord of juvenile tilapia. Eighty-four fish were divided into seven groups: group 1 fish acted as controls and the remaining fish were exposed to sublethal concentrations of acetochlor, bispyribac-sodium, bentazon, bensulfuron-methyl, halosulfuron-methyl, or quinclorac at sublethal concentrations 2.625, 0.800, 36.00, 2.50, 1.275, and 11.250 mg/l, respectively, for 96 h. Antioxidant parameters changed in response to some test herbicides and the greatest effects were caused by exposure to acetochlor and quinelorac for all antioxidant measurements. Prominent histological changes in liver tissue included loss of liver architecture and the appearance of fatty liver cells, necrotic areas, foci of leukocytic infiltration and many apoptotic cells. The most obvious changes in the spinal cord in all treated fish were degradation of myelinated white matter fibers with the emergence of empty spaces, large aggregation of pyknotic neuroglial nuclei, and damaged areas in the dorsal horn of gray matter. Collectively, the harmful effect of tested herbicides on antioxidant capacity and significant alterations in histological structures of liver and spinal cord of Oreochromis niloticus.

目前的研究估计了不同常见除草剂对罗非鱼幼鱼肝脏和脊髓的抗氧化防御和组织学结构的影响。将 84 条鱼分为 7 组：第 1 组鱼作为对照，其余鱼暴露于亚致死浓度为 2.625、0.800 的乙草胺、双嘧磺草胺、苯达松、苯磺隆、氟磺隆或二氯喹啉、36.00、2.50、1.275 和 11.250 毫克/升，分别为 96 H。抗氧化参数随着一些测试除草剂的变化而变化，并且在所有抗氧化测量中，最大的影响是由暴露于乙草胺和喹诺酸引起的。肝组织的显着组织学变化包括肝脏结构的丧失和脂肪肝细胞、坏死区、白细胞浸润病灶和许多凋亡细胞的出现。在所有处理过的鱼中，脊髓最明显的变化是有髓白质纤维退化，出现空白，大量固缩神经胶质细胞核聚集，灰质背角受损区域。总的来说，测试的除草剂对尼罗罗非鱼的抗氧化能力和肝脏和脊髓组织学结构的显着改变的有害影响。