Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition,Cancer Cell

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Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition
Cancer Cell ( IF 50.3 ) Pub Date : 2022-04-28 , DOI: 10.1016/j.ccell.2022.04.009
Justin T Low ₁ , Vidyalakshmi Chandramohan ₁ , Michelle L Bowie ₁ , Michael C Brown ₁ , Matthew S Waitkus ₁ , Aaron Briley ₁ , Kevin Stevenson ₂ , Rebecca Fuller ₁ , Zachary J Reitman ₃ , Andrea M Muscat ₄ , Seethalakshmi Hariharan ₁ , Janell Hostettler ₁ , Sarah Danehower ₅ , Ali Baker ₆ , Mustafa Khasraw ₁ , Nicholas C Wong ₇ , Simon Gregory ₂ , Smita K Nair ₈ , Amy Heimberger ₉ , Matthias Gromeier ₁₀ , Darell D Bigner ₁ , David M Ashley ₁

Affiliation

Department of Neurosurgery, Duke University Medical School, Durham, NC, USA.
Molecular Physiology Institute, Duke University Medical School, Durham, NC, USA.
Department of Radiation Oncology, Duke University Medical School, Durham, NC, USA.
Department of Neurosciences, Monash University, Melbourne, VIC, Australia; Department of Neurology, Alfred Health, Melbourne, VIC, Australia.
Department of Neurological Surgery, University of Louisville, Louisville, KY, USA.
Department of Neurosciences, Monash University, Melbourne, VIC, Australia.
Monash Bioinformatics Platform, Monash University, Clayton, VIC, Australia.
Department of Neurosurgery, Duke University Medical School, Durham, NC, USA; Department of Surgery, Duke University Medical School, Durham, NC, USA; Department of Pathology, Duke University Medical School, Durham, NC, USA.
Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Department of Neurosurgery, Duke University Medical School, Durham, NC, USA; Department of Molecular Genetics & Microbiology, Duke University Medical School, Durham, NC, USA.