Laccases have been in the spotlight due to its capability to catalyse electrocatalytic reactions. Its ability to reduce water to oxygen has made it more bio-compatible than majority of electrocatalysts. The exploitation of such biocatalysts via protein engineering and biotechnological techniques have rendered a significant breakthrough in the field of electrocatalysis. This review aims to provide a comprehensive overview of the various laccase-driven electrocatalytic reactions. Structural and functional features of laccases that contribute towards the electron transfer mechanism and reduction potential have been meticulously described. Tailoring of laccase affords an excellent prospect for its application in diverse fields like, biocathode fabrication for enzymatic biofuel cells, biosensors, and electrocatalytic reactions like water splitting. The substantial knowledge of enzyme engineering, primarily through site directed mutagenesis is propitious for the design of optimal bioelectrocatalyst. This review seeks to provide an insight for the optimisation of electrocatalytic properties of laccase thereby broadening the horizon for the development of resilient and biocompatible bioelectrocatalyst.

漆酶因其催化电催化反应的能力而备受关注。其将水还原为氧气的能力使其比大多数电催化剂更具生物相容性。通过蛋白质工程和生物技术开发这种生物催化剂，在电催化领域取得了重大突破。本综述旨在全面概述各种漆酶驱动的电催化反应。已经详细描述了有助于电子转移机制和还原电位的漆酶的结构和功能特征。漆酶的定制为其在酶生物燃料电池的生物阴极制造、生物传感器和水分解等电催化反应等不同领域的应用提供了良好的前景。酶工程的大量知识，主要是通过定点诱变，有利于设计最佳的生物电催化剂。本综述旨在为优化漆酶的电催化性能提供见解，从而拓宽开发弹性和生物相容性生物电催化剂的视野。