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A Presurgical-Window Intervention Trial of Isothiocyanate-Rich Broccoli Sprout Extract in Patients with Breast Cancer
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2022-04-27 , DOI: 10.1002/mnfr.202101094
Zinian Wang 1 , Chengjian Tu 2 , Rachel Pratt 1 , Thaer Khoury 3 , Jun Qu 2 , Jed W Fahey 4, 5 , Susan E McCann 1 , Yuesheng Zhang 6 , Yue Wu 7 , Alan D Hutson 8 , Christine B Ambrosone 1 , Stephen B Edge 9 , Helen H Cappuccino 9 , Kazuaki Takabe 9 , Jessica S Young 9 , Li Tang 1
Affiliation  

Dietary isothiocyanates (ITCs) from cruciferous vegetables have shown potent anti-breast cancer activities in preclinical models, but their anticancer effects in vivo in breast cancer patients remain elusive. A proof-of-principle, presurgical window of opportunity trial is conducted to assess the anticancer effects of dietary ITCs in breast cancer patients.

中文翻译:

富含异硫氰酸盐的西兰花芽提取物对乳腺癌患者进行术前窗口干预试验

来自十字花科蔬菜的膳食异硫氰酸盐 (ITC) 在临床前模型中显示出有效的抗乳腺癌活性,但其在乳腺癌患者体内的抗癌作用仍然难以捉摸。进行了原理验证、术前机会窗口试验,以评估饮食 ITC 对乳腺癌患者的抗癌作用。
更新日期:2022-04-27
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