The ability of immune cells to penetrate affected tissues is highly dependent on energy provided by mitochondria, yet their involvement in promoting migration remains unclear. Recent work by Emtenani et al (2022) describes a nuclear Atossa-Porthos axis that adjusts transcription and translation of a small subset of OXPHOS genes to increase mitochondrial bioenergetics and allow macrophage tissue invasion in flies.

中文翻译：

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Atossa：OXPHOS 代谢和巨噬细胞迁移之间的皇家联系

免疫细胞穿透受影响组织的能力高度依赖于线粒体提供的能量，但它们参与促进迁移仍不清楚。Emtenani等人(2022) 最近的工作描述了一个核 Atossa-Porthos 轴，它调整一小部分 OXPHOS 基因的转录和翻译，以增加线粒体生物能量学并允许巨噬细胞组织侵入果蝇。