The introduction of highly active combined antiretroviral therapy (cART) has changed the management of HIV/AIDS, which is recognized as a chronic disease with relevant aspects, such as adherence and quality of life. This study aimed to compare clinical and demographic characteristics and health-related quality of life in people with adherence and non-adherence to cART. A cross-sectional study was carried out with 200 participants. The instruments used were the Adherence Follow-up Questionnaire, the Beck Depression Inventory-II, the 36-Item Short Form Health Survey and the WHOQOL-HIV BREF. Poisson regression was applied to obtain estimates of adjusted prevalence ratios (PR_adj). Individuals lacking therapeutic support were more likely to be non-adherent than those with proper support (PR: 1.79). The health-related quality of life of individuals with non-adherence was 4% lower (PR = 0.96) in the general health domain than individuals with adherence. Non-adherence to cART was associated with lower quality of life in the general health domain and no therapeutic support.

中文翻译：

---

生活质量和抗逆转录病毒疗法的依从性：哥伦比亚的一项横断面研究

高效联合抗逆转录病毒疗法 (cART) 的引入改变了 HIV/AIDS 的管理，HIV/AIDS 被认为是一种慢性疾病，具有相关方面，例如依从性和生活质量。本研究旨在比较坚持和不坚持 cART 的人的临床和人口统计学特征以及与健康相关的生活质量。对 200 名参与者进行了横断面研究。使用的工具是依从性随访问卷、Beck 抑郁量表-II、36 项短期健康调查和 WHOQOL-HIV BREF。应用泊松回归来估计调整后的患病率（PR _adj). 缺乏治疗支持的个体比获得适当支持的个体更可能不依从（PR：1.79）。在一般健康领域，不依从者的健康相关生活质量比依从者低 4% (PR = 0.96)。不遵守 cART 与一般健康领域较低的生活质量和没有治疗支持有关。