Significance Rational control of arthropod pests is important for animal and human health as well as biodiversity preservation. As an alternative to synthetic chemical pesticides, natural repellents represent an ecological method of pest control. Through an exceptional gene library screening in Mesobuthus martensii scorpions, we here uncover a transient receptor potential ion channel as the chemosensory sensor for plant-derived repellents. Its ortholog ion channel in Drosophila melanogaster also acts as a molecular receptor of natural repellents and mediates avoidance behavior. This work thus identifies a molecular basis for arthropod chemosensing and should help update the ecological strategies for pest control while preserving biodiversity.

中文翻译：

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鉴定植物来源的天然驱虫剂的节肢动物分子靶标

意义合理控制节肢动物害虫对动物和人类健康以及生物多样性保护具有重要意义。作为合成化学杀虫剂的替代品，天然驱虫剂代表了一种害虫防治的生态方法。通过一个特殊的基因库筛选马氏青蛙蝎子，我们在这里发现了一个瞬时受体电位离子通道作为植物来源驱虫剂的化学感应传感器。它的直系同源离子通道在果蝇也充当天然驱虫剂的分子受体并介导回避行为。因此，这项工作确定了节肢动物化学传感的分子基础，应该有助于更新害虫防治的生态策略，同时保护生物多样性。