Two recent large-cohort studies reinforce the potential predictive capability of gut microbiota for immune-checkpoint inhibitor response and toxicities in patients with melanoma. However, additional investigations are required to understand the mechanistic underpinnings of this complex multifaceted relationship, and how it can be exploited for personalized cancer care.

中文翻译：

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肠道微生物作为 ICI 反应的生物标志物——聚焦焦点

最近的两项大型队列研究加强了肠道微生物群对黑色素瘤患者免疫检查点抑制剂反应和毒性的潜在预测能力。然而，需要进行额外的调查以了解这种复杂的多方面关系的机制基础，以及如何将其用于个性化癌症护理。