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Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures.
Bone & Joint Research ( IF 4.6 ) Pub Date : 2022-4-21 , DOI: 10.1302/2046-3758.114.bjr-2021-0226.r1
Christopher C Stewart 1 , Nathan N O'Hara 2 , Sofia Bzovsky 3 , Chelsea S Bahney 4, 5 , Sheila Sprague 3, 6 , Gerard P Slobogean 2 ,
Affiliation  

Bone turnover markers (BTMs) follow distinct trends after fractures and limited evidence suggests differential levels in BTMs in patients with delayed healing. The effect of vitamin D, and other factors that influence BTMs and fracture healing, is important to elucidate the use of BTMs as surrogates of fracture healing. We sought to determine whether BTMs can be used as early markers of delayed fracture healing, and the effect of vitamin D on BTM response after fracture.

中文翻译:

骨转换标志物作为胫骨和股骨骨折髓内固定后骨折愈合的替代指标。

骨折后骨转换标志物 (BTMs) 遵循不同的趋势,有限的证据表明延迟愈合患者的 BTMs 水平不同。维生素 D 的作用以及影响 BTM 和骨折愈合的其他因素对于阐明 BTM 作为骨折愈合替代物的使用非常重要。我们试图确定 BTM 是否可用作骨折延迟愈合的早期标志物,以及维生素 D 对骨折后 BTM 反应的影响。
更新日期:2022-04-21
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