A short thumb with radial angulation causes loss of hand function in patients with Apert syndrome. Although past reports have described various procedures for the correction of the thumb, there has been no consensus on the best procedure. This study aimed to assess the clinical and radiographic results of a surgical technique for the correction of a thumb radial angulation deformity: open-wedge osteotomy using a bone-graft substitute. Ten patients (18 thumbs) who underwent open-wedge osteotomy on the proximal phalange using a bone-graft substitute were evaluated retrospectively. The open-wedge osteotomies had been performed at the center of the proximal phalanx. Thumb radial angles and thumb lengths were measured on radiographs, and the clinical results were investigated, including bone union and complications. The median patient age at the time of surgery was 5.8 years, and the average follow-up period was 6.7 years. The average thumb radial angle was 57.3° preoperatively, 6.5° immediately postoperatively, and 19.8° at the most recent follow-up. The average thumb length was 12.1 mm preoperatively, 18.1 mm immediately postoperatively, and 22.3 mm at the most recent follow-up, indicating an extension effect of more than 50% immediately postoperatively. In all cases, the artificial bone had been absorbed and developed into autologous bone, and there were no complications such as infection and skin necrosis. These findings suggest that open-wedge osteotomy with an artificial bone substitute is simple and effective for treating radial-angulation deformities in patients with Apert syndrome. Level of evidence: Level IV – retrospective case series.

具有径向角度的短拇指会导致阿佩尔综合征患者手部功能丧失。尽管过去的报告描述了各种拇指矫正手术，但对于最佳手术尚未达成共识。本研究旨在评估矫正拇指桡骨成角畸形的手术技术的临床和放射学结果：使用骨移植替代物的开放楔形截骨术。对使用骨移植替代物在近端指骨上接受开放楔形截骨术的 10 名患者（18 个拇指）进行了回顾性评估。开放楔形截骨术是在近节指骨的中心进行的。在X光片上测量拇指桡角和拇指长度，并调查临床结果，包括骨愈合和并发症。手术时患者的中位年龄为 5.8 岁，平均随访时间为 6.7 年。术前平均拇指桡角为57.3°，术后即刻为6.5°，最近一次随访时为19.8°。术前拇指平均长度为12.1毫米，术后即刻为18.1毫米，最近一次随访时为22.3毫米，术后即刻伸展效果超过50%。所有病例中人工骨均已被吸收并发育为自体骨，且未出现感染、皮肤坏死等并发症。这些研究结果表明，使用人工骨替代物的开放楔形截骨术对于治疗阿佩尔综合征患者的桡骨成角畸形来说简单而有效。证据级别：IV 级——回顾性病例系列。