Background Increased age and cognitive impairment is associated with an increase in cerebrovascular pathology often measured as white matter hyperintensities (WMHs) on MRI. Whether WMH burden differs between cognitively unimpaired older adults with subjective cognitive decline (SCD+) and without subjective cognitive decline (SCD–) remains conflicting, and could be related to the methods used to identify SCD. Our goal was to examine if four common SCD classification methods are associated with different WMH accumulation patterns between SCD+ and SCD-.

中文翻译：

---

白质高信号负荷因主观认知衰退标准而异

背景年龄增加和认知障碍与脑血管病变的增加有关，通常以 MRI 上的白质高信号 (WMH) 来衡量。具有主观认知能力下降 (SCD+) 和没有主观认知能力下降 (SCD–) 的认知未受损老年人之间的 WMH 负担是否不同仍然存在矛盾，并且可能与用于识别 SCD 的方法有关。我们的目标是检查四种常见的 SCD 分类方法是否与 SCD+ 和 SCD- 之间的不同 WMH 积累模式相关。