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Chemo-Enzymatic Modification of the 5′ Cap To Study mRNAs
Accounts of Chemical Research ( IF 18.3 ) Pub Date : 2022-04-14 , DOI: 10.1021/acs.accounts.2c00059
Amarnath Bollu 1 , Aileen Peters 1 , Andrea Rentmeister 1
Affiliation  

The central dogma of molecular biology hinges on messenger RNA (mRNA), which presents a blueprint of the genetic information encoded in the DNA and serves as a template for translation into proteins. In addition to its fundamental importance in basic research, this class of biomolecules has recently become the first approved Covid vaccine, underscoring its utility in medical applications.

中文翻译:

5' 帽的化学酶修饰以研究 mRNA

分子生物学的中心法则取决于信使 RNA (mRNA),它呈现了 DNA 中编码的遗传信息的蓝图,并作为翻译成蛋白质的模板。除了在基础研究中的根本重要性外,这类生物分子最近还成为第一个获批的 Covid 疫苗,强调了其在医疗应用中的实用性。
更新日期:2022-04-14
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