Alzheimer's disease accounts for a high percentage of dementia cases in elderly individuals. This type of brain disease is caused by damage to the brain cells affecting the ability of the patients to communicate, as well as their thinking, behavior, and feelings. Although numerous research laboratories focus on advancements in treating Alzheimer's disease, the currently approved pharmacological approaches seem to only alleviate the symptoms. Consequently, there is an urgent need for alternative pharmacological options that can prevent the progressive impairment of neurons. Natural substances were used in ancient times to treat various disorders given their biological activities such as antioxidant, anti-inflammatory, and antiapoptotic properties. Besides, their cost-effectiveness and accessibility to anyone who needs them are their most significant characteristics. Therefore, the possible use of phytochemical compounds for the possible management or even prevention of Alzheimer's disease is currently under investigation. This review article summarizes the present status of Alzheimer's disease diagnosis and underlying mechanisms, the potential phytochemicals and their carriers, along with future perspectives. In the future, natural substances can play a role as an adjunct therapy for neurodegenerative forms of dementia, such as Alzheimer's disease.

中文翻译：

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加载到纳米载体上的植物化学化合物作为阿尔茨海默病的潜在治疗物质——它们会有效吗？

阿尔茨海默病在老年人痴呆病例中占很大比例。这种类型的脑部疾病是由脑细胞受损引起的，影响患者的交流能力，以及他们的思维、行为和感受。尽管许多研究实验室专注于治疗阿尔茨海默病的进展，但目前批准的药理学方法似乎只能缓解症状。因此，迫切需要可以防止神经元进行性损伤的替代药理学选择。天然物质在古代被用于治疗各种疾病，因为它们具有抗氧化、抗炎和抗凋亡等生物活性。除了，它们的成本效益和对任何需要它们的人的可及性是它们最重要的特征。因此，目前正在研究将植物化学化合物用于可能的管理甚至预防阿尔茨海默病的可能性。这篇综述文章总结了阿尔茨海默病诊断的现状和潜在机制、潜在的植物化学物质及其载体，以及未来的展望。将来，天然物质可以作为神经退行性痴呆症（如阿尔茨海默病）的辅助疗法发挥作用。这篇综述文章总结了阿尔茨海默病诊断的现状和潜在机制、潜在的植物化学物质及其载体，以及未来的展望。将来，天然物质可以作为神经退行性痴呆症（如阿尔茨海默病）的辅助疗法发挥作用。这篇综述文章总结了阿尔茨海默病诊断的现状和潜在机制、潜在的植物化学物质及其载体，以及未来的展望。将来，天然物质可以作为神经退行性痴呆症（如阿尔茨海默病）的辅助疗法发挥作用。