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Ultrasound-guided platelet-rich-plasma injections for reducing sacroiliac joint pain: A paradigmatic case report and literature review
Journal of Back and Musculoskeletal Rehabilitation ( IF 1.6 ) Pub Date : 2022-04-07 , DOI: 10.3233/bmr-210310
Alessandro de Sire 1 , Lorenzo Lippi 2 , Kamal Mezian 3 , Dario Calafiore 4 , Raffaello Pellegrino 5 , Gennaro Mascaro 6 , Carlo Cisari 2 , Marco Invernizzi 1, 7
Affiliation  

BACKGROUND: Sacro-iliac joint (SIJ) pain is an often-misdiagnosed cause (up to 30% cases) of atypical low back pain (LBP) that might be treated with a wide range of conservative interventions. However, Platelet-Rich-Plasma (PRP) ultrasound-guided injections at SIJ level in subjects with mitochondrial disorders have not yet been investigated. CASE PRESENTATION: A 52-year-old Caucasian male with fluoroquinolone-related mitochondrial dysfunction referred to a Physical Medicine and Rehabilitation Outpatient, complaining of severe SIJ pain (Numeric Pain Related Scale, NPRS=8). We performed two bilateral PRP ultrasound-guided injections at the sacro-iliac level. PRP is a simple, efficient, and minimally invasive approach. After the first PRP injection, there was a considerable reduction of pain (NPRS=8 vs 5). The second PRP infiltration was performed after 2 weeks and in both cases no adverse events. At the 6-month follow-up evaluation, the patient showed good physical recovery, with the absence of pain (NPRS=0). CONCLUSION: To the best of our knowledge, this is the first report in the literature assessing the safety and effectiveness of PRP ultrasound-guided injections for SIJ pain in a patient affected by mitochondrial disorders. Thus, this case report might have relevant clinical implications in the treatment of SIJ pain in patients affected by this rare pathological condition, albeit further observational studies are warranted to confirm these findings.

中文翻译:

超声引导下富血小板血浆注射减轻骶髂关节疼痛:典型病例报告和文献回顾

背景:骶髂关节 (SIJ) 疼痛是非典型腰痛 (LBP) 的一个经常被误诊的原因(高达 30% 的病例),可以通过广泛的保守干预来治疗。然而,尚未对患有线粒体疾病的受试者进行 SIJ 水平的富血小板血浆 (PRP) 超声引导注射。病例介绍:一名患有与氟喹诺酮类药物相关的线粒体功能障碍的 52 岁白人男性被转诊到物理医学和康复门诊,主诉严重的 SIJ 疼痛(数字疼痛相关量表,NPRS=8)。我们在骶髂水平进行了两次双侧 PRP 超声引导注射。PRP 是一种简单、有效且微创的方法。第一次 PRP 注射后,疼痛明显减轻(NPRS=8 vs 5)。第二次 PRP 浸润在 2 周后进行,在这两种情况下都没有不良事件。在 6 个月的随访评估中,患者身体恢复良好,无疼痛(NPRS=0)。结论:据我们所知,这是文献中第一份评估 PRP 超声引导注射治疗受线粒体疾病影响的患者 SIJ 疼痛的安全性和有效性的报告。因此,该病例报告可能对受这种罕见病理状况影响的患者的 SIJ 疼痛的治疗具有相关的临床意义,尽管需要进一步的观察性研究来证实这些发现。据我们所知,这是文献中第一份评估 PRP 超声引导注射对受线粒体疾病影响的患者的 SIJ 疼痛的安全性和有效性的报告。因此,该病例报告可能对受这种罕见病理状况影响的患者的 SIJ 疼痛的治疗具有相关的临床意义,尽管需要进一步的观察性研究来证实这些发现。据我们所知,这是文献中第一份评估 PRP 超声引导注射对受线粒体疾病影响的患者的 SIJ 疼痛的安全性和有效性的报告。因此,该病例报告可能对受这种罕见病理状况影响的患者的 SIJ 疼痛的治疗具有相关的临床意义,尽管需要进一步的观察性研究来证实这些发现。
更新日期:2022-04-07
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