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Ingested Foreign Bodies Can Cause Appendicitis and Perforation: A Multi-Institutional Case Series.
Pediatric and Developmental Pathology ( IF 1.9 ) Pub Date : 2022-04-11 , DOI: 10.1177/10935266221083188
Maren Y Fuller 1 , Daniel G Leino 2 , Miguel Reyes-Múgica 3 , Alexandra E Kovach 4, 5 , José E Velázquez Vega 6 , Shelley Caltharp 6 , Tricia Bhatti 7 , Raul S Gonzalez 8
Affiliation  

INTRODUCTION Appendicular foreign bodies are a rare, under-described cause of appendicitis. We performed this study to determine the varied causes and consequences of foreign-body appendicitis. METHODS On retrospective review of the pathology archives of seven institutions, we identified 56 appendix specimens containing a foreign body (defined as ingested, non-digestible material). We recorded the type of foreign body, patient age and sex, and other findings, as available. RESULTS Mean patient age was 7.7 years (range: 1 day-18 years). The foreign bodies included hair, plant material, magnets, other metallic material, BB pellets, foreign material not otherwise specified, and other miscellaneous objects. Of 48 cases with available clinical information, 31 patients presented with abdominal pain, and 22 were preoperatively diagnosed as having appendicitis/appendicular inflammation. Seven patients had appendiceal perforation (13%). The foreign body was grossly identified in 34/47 cases with available gross descriptions. Twenty-seven cases had an identifiable foreign body microscopically; 10 were associated with giant cell reaction. DISCUSSION Hair and plant materials were the most common foreign objects found in the appendix; they often cause mucosal damage and giant cell reaction. Metallic objects were less common. Although appendicular foreign bodies in children are rare and sometimes asymptomatic, they may lead to perforation.

中文翻译:

摄入异物可导致阑尾炎和穿孔:多机构病例系列。

引言 阑尾异物是一种罕见的、未充分描述的阑尾炎病因。我们进行了这项研究以确定异物阑尾炎的各种原因和后果。方法 在对七家机构的病理档案进行回顾性审查时,我们确定了 56 份含有异物(定义为摄入的、不可消化的物质)的阑尾标本。我们记录了异物的类型、患者的年龄和性别,以及其他可用的结果。结果 患者平均年龄为 7.7 岁(范围:1 天至 18 岁)。异物包括头发、植物材料、磁铁、其他金属材料、BB 颗粒、未另行指定的异物和其他杂物。在有可用临床信息的 48 例患者中,31 例患者出现腹痛,22例术前诊断为阑尾炎/阑尾炎。七名患者有阑尾穿孔(13%)。在 34/47 的病例中,有可用的大体描述可以大体识别出异物。27例镜下可识别异物;10 与巨细胞反应有关。讨论 头发和植物材料是附录中最常见的异物;它们经常引起粘膜损伤和巨细胞反应。金属物体不太常见。尽管儿童的阑尾异物很少见,有时无症状,但它们可能会导致穿孔。27例镜下可识别异物;10 与巨细胞反应有关。讨论 头发和植物材料是附录中最常见的异物;它们经常引起粘膜损伤和巨细胞反应。金属物体不太常见。尽管儿童的阑尾异物很少见,有时无症状,但它们可能会导致穿孔。27例镜下可识别异物;10 与巨细胞反应有关。讨论 头发和植物材料是附录中最常见的异物;它们经常引起粘膜损伤和巨细胞反应。金属物体不太常见。尽管儿童的阑尾异物很少见,有时无症状,但它们可能会导致穿孔。
更新日期:2022-04-11
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