In electrochemical immunoassays, great breakthroughs have been made in ultrasensitive detection of tumor markers by amplifying signals with coreaction accelerators. Herein, carbon nitrides with nitrogen vacancies (CNNVs) are proposed as emitter, due to the introduction of nitrogen vacancies this emitter has better ECL efficiency, the phenomena of interface electron transfer and electrode passivation are improved. At the same time, it can also promote the electrochemical reduction of coreactant, making it an attractive and potential emitter. The electrode was modified with Ag-Ti₃C₂ MXene. It not only accelerates electron transfer and increases the effective working area of the electrode, but also acts as a coreaction accelerator to promote the electrochemical reduction of the coreactant K₂S₂O₈, resulting in a strong ECL signal. The immunosensor showed a good linear relationship in the range of 10⁻⁵-100 ng/mL with a detection limit of 0.36 fg/mL. In addition, the excellent properties of good specificity and ultra-high stability provide an effective method for ultra-sensitive immunoassays.

在电化学免疫分析中，通过共反应加速器放大信号，在超灵敏检测肿瘤标志物方面取得了重大突破。在此，提出了具有氮空位的氮化碳（CNNVs）作为发射极，由于氮空位的引入，该发射极具有更好的ECL效率，改善了界面电子转移和电极钝化现象。同时，它还可以促进共反应物的电化学还原，使其成为具有吸引力和潜力的发射体。电极用 Ag-Ti ₃ C _2改性MXene。它不仅加速电子转移，增加电极的有效工作面积，而且作为共反应促进剂，促进共反应物K ₂ S ₂ O ₈的电化学还原，产生强烈的ECL信号。^{该免疫传感器在10 -5} -100 ng/mL范围内表现出良好的线性关系，检测限为0.36 fg/mL。此外，良好的特异性和超高稳定性的优良特性为超灵敏免疫测定提供了有效的方法。