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An environmentally benign multi-component reaction: Highly regioselective synthesis of functionalized 2-(diarylphosphoryl)-1,2-dihydro-pyridine derivatives
Green Synthesis and Catalysis Pub Date : 2022-2-1 , DOI: 10.1016/j.gresc.2021.10.008
Kun Li , Ying Lv , Zihan Lu , Xinghan Yun , Shengjiao Yan

A novel protocol was developed for the construction of highly functionalized 2-(diarylphosphoryl)-1,2-dihydropyridine derivatives (DAPDHPs) from 3-formylchromones (1), heterocyclic ketal aminals (HKAs, 2), and phosphine oxides (R2P(O)H, 3) via a novel, one-pot cascade reaction.

中文翻译:

一种环境友好的多组分反应:功能化 2-(二芳基磷酰基)-1,2-二氢-吡啶衍生物的高度区域选择性合成

开发了一种新的方案,用于从 3-甲酰色酮 (1)、杂环缩酮缩醛胺 (HKAs, 2) 和氧化膦 (R2P(O )H, 3) 通过一种新颖的一锅级联反应。
更新日期:2022-03-28
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