Glutamate (Glu) and γ-aminobutyric acid (GABA) are the major excitatory and inhibitory neurotransmitters that control information flow in the brain. GABA dysfunction is a general vulnerability factor for mental illness. Cinnamaldehyde (CA) is found to have sedation in a mental illness model. However, the specific targets and molecular mechanisms related to the sedative effects of CA have not been elucidated.

中文翻译：

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肉桂醛通过对小脑颗粒层 ENO1 的不可逆抑制来调节 γ-氨基丁酸的产生以发挥镇静作用

谷氨酸 (Glu) 和 γ-氨基丁酸 (GABA) 是控制大脑信息流的主要兴奋性和抑制性神经递质。GABA 功能障碍是精神疾病的普遍易感因素。肉桂醛 (CA) 在精神疾病模型中被发现具有镇静作用。然而，与 CA 的镇静作用相关的具体靶点和分子机制尚未阐明。