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Assessing the role of socioeconomic status and discrimination exposure for racial disparities in inflammation
Brain, Behavior, and Immunity ( IF 15.1 ) Pub Date : 2022-03-17 , DOI: 10.1016/j.bbi.2022.03.005
Adolfo G Cuevas 1 , Evan Goler 1 , Claudia J Guetta 1 , Robert F Krueger 2
Affiliation  

Socioeconomic status (SES) and discrimination have been implicated as social determinants of health and health disparities. Yet, very little research has been done to assess their contributing role in Black-White disparities in inflammation. Using data from the Midlife in the United States (2004–2006), we conducted Oaxaca-Blinder decomposition analysis to quantify the extent to which three indicators of SES (i.e., education, household income, and employment status) and three forms of discrimination exposures (i.e., everyday, lifetime, and workplace discrimination) explained Black-White differences in inflammation. Education, particularly having a college degree or more, explained 16.88% of the differences between Blacks and Whites. There was no evidence that household income and employment status explained Black-White inflammation differences. Lifetime discrimination significantly explained 18.18% of Black-White difference in inflammation burden. There was no evidence that everyday and workplace discrimination explained Black-White difference in inflammation burden. Together, the predictors explained 44.16% of inflammation differences between Black and White participants. Education and lifetime exposure to discrimination may play a role in inflammation disparities. Further research is needed to examine other dimensions of SES (e.g., wealth) and discrimination (e.g., racial segregation) that are associated with health to better understand the contributions of these key social determinants of Black-White inflammation disparities.



中文翻译:

评估社会经济地位和歧视暴露对炎症种族差异的影响

社会经济地位(SES)和歧视被认为是健康和健康差异的社会决定因素。然而,很少有研究来评估它们在炎症中黑白差异中的作用。利用美国中年时期(2004-2006)的数据,我们进行了 Oaxaca-Blinder 分解分析,以量化 SES 的三个指标(即教育、家庭收入和就业状况)和三种形式的歧视暴露程度(即日常生活、一生和工作场所的歧视)解释了炎症中黑人和白人的差异。教育,特别是拥有大学或以上学位,解释了黑人和白人之间 16.88% 的差异。没有证据表明家庭收入和就业状况可以解释黑人与白人的炎症差异。终生歧视显着解释了黑人与白人炎症负担差异的 18.18%。没有证据表明日常和工作场所的歧视可以解释黑人与白人炎症负担的差异。这些预测因子共同解释了黑人和白人参与者之间 44.16% 的炎症差异。教育程度和终生遭受歧视可能会导致炎症差异。需要进一步的研究来检查与健康相关的社会经济地位(例如财富)和歧视(例如种族隔离)的其他方面,以更好地了解这些黑人与白人炎症差异的关键社会决定因素的贡献。

更新日期:2022-03-17
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