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Inhibiting GLUTtony in cancer
Cell Chemical Biology ( IF 8.6 ) Pub Date : 2022-03-17 , DOI: 10.1016/j.chembiol.2022.03.004 Sarah M Chang 1 , Matthew G Vander Heiden 2
中文翻译:
抑制癌症中的 GLUTtony
更新日期:2022-03-17
Cell Chemical Biology ( IF 8.6 ) Pub Date : 2022-03-17 , DOI: 10.1016/j.chembiol.2022.03.004 Sarah M Chang 1 , Matthew G Vander Heiden 2
Affiliation
In this issue of Cell Chemical Biology, Olszewski et al. (2022) address the challenge of developing small molecules to inhibit glucose uptake in cancer. They characterize a novel pan-GLUT inhibitor that suppresses tumor growth and uncover how cancer cells can adapt to glucose restriction.
中文翻译:
抑制癌症中的 GLUTtony
在本期细胞化学生物学中,Olszewski 等人。(2022)解决开发小分子以抑制癌症中葡萄糖摄取的挑战。他们描述了一种抑制肿瘤生长的新型泛 GLUT 抑制剂,并揭示了癌细胞如何适应葡萄糖限制。