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TCMPG: an integrative database for traditional Chinese medicine plant genomes
Horticulture Research ( IF 8.7 ) Pub Date : 2022-05-17 , DOI: 10.1093/hr/uhac060
Fanbo Meng 1, 2 , Qiang Tang 1, 3 , Tianzhe Chu 1, 4 , Xianhai Li 1, 4 , Yue Lin 1, 3 , Xiaoming Song 5 , Wei Chen 1, 2, 3, 5
Affiliation  

Because of their great therapeutic and economic value, medicinal plants have attracted increasing scientific attention. With the rapid development of high-throughput sequencing technology, the genomes of many medicinal plants have been sequenced. Storing and analyzing the increasing volume of genomic data has become an urgent task. To solve this challenge, we have proposed the Traditional Chinese Medicine Plant Genome database (TCMPG, http://cbcb.cdutcm.edu.cn/TCMPG/), an integrative database for storing the scattered genomes of medicinal plants. TCMPG currently includes 160 medicinal plants, 195 corresponding genomes, and 255 herbal medicines. Detailed information on plant species, genomes, and herbal medicines is also integrated into TCMPG. Popular genomic analysis tools are embedded in TCMPG to facilitate the systematic analysis of medicinal plants. These include BLAST for identifying orthologs from different plants, SSR Finder for identifying simple sequence repeats, JBrowse for browsing genomes, Synteny Viewer for displaying syntenic blocks between two genomes, and HmmSearch for identifying protein domains. TCMPG will be continuously updated by integrating new data and tools for comparative and functional genomic analysis.

中文翻译:

TCMPG:中药植物基因组综合数据库

由于其巨大的治疗和经济价值,药用植物引起了越来越多的科学关注。随着高通量测序技术的快速发展,许多药用植物的基因组已经被测序。存储和分析越来越多的基因组数据已成为一项紧迫的任务。为了解决这一挑战,我们提出了中药植物基因组数据库(TCMPG,http://cbcb.cdutcm.edu.cn/TCMPG/),这是一个用于存储药用植物分散基因组的综合数据库。TCMPG 目前包括 160 种药用植物、195 种相应的基因组和 255 种草药。植物物种、基因组和草药的详细信息也被整合到 TCMPG 中。TCMPG 中嵌入了流行的基因组分析工具,以促进药用植物的系统分析。其中包括用于识别来自不同植物的直系同源物的 BLAST、用于识别简单序列重复的 SSR Finder、用于浏览基因组的 JBrowse、用于显示两个基因组之间的同线性块的 Synteny Viewer 以及用于识别蛋白质结构域的 HmmSearch。TCMPG 将通过整合用于比较和功能基因组分析的新数据和工具来不断更新。
更新日期:2022-05-17
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