Atmospheric low-temperature plasma has received attention for application in disinfection methods. In this study, we develop a plasma bubbling method as a disinfection method. In the plasma bubbling method, the bactericidal effect can be introduced into the water by bubbling with carbon dioxide plasma. The plasma bubbling method is effective for the treatment of Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Serratia marcescens, and Fusarium solani, which pose problems in the field of ophthalmology. In addition, we develop ultrasonic-combined plasma bubbling, in which plasma bubbling imposes a bactericidal effect, whereas ultrasonic exerts a detachment effect as a disinfection method for adherent bacteria on medical equipment. Ultrasonic-combined plasma bubbling demonstrates a prominent bactericidal effect on P. aeruginosa adherent bacteria on stainless steel plates and can be used to the measuring prism (MP) of applanation tonometers. In observation the MP treated with plasma bubbling and ultrasonic-combined plasma bubbling for 11 h, no damage to the MPs was observed.

常压低温等离子体在消毒方法中的应用受到关注。在这项研究中，我们开发了一种等离子鼓泡法作为消毒方法。在等离子体鼓泡法中，可以通过用二氧化碳等离子体鼓泡将杀菌效果引入水中。等离子鼓泡法对金黄色葡萄球菌、铜绿假单胞菌、白色念珠菌、粘质沙雷氏菌和茄病镰刀菌有效。，这给眼科领域带来了问题。此外，我们还开发了超声波联合等离子体鼓泡，其中等离子体鼓泡具有杀菌作用，而超声波则具有剥离作用，作为医疗设备上附着细菌的消毒方法。超声波联合等离子体鼓泡对不锈钢板上的铜绿假单胞菌粘附细菌具有显着的杀菌作用，可用于压平眼压计的测量棱镜（MP）。在观察用等离子体鼓泡和超声组合等离子体鼓泡处理 11 小时的 MP 中，没有观察到 MP 的损坏。