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Putting Genetics to Work in the Psychiatric Clinic
American Journal of Psychiatry ( IF 17.7 ) Pub Date : 2022-03-03 , DOI: 10.1176/appi.ajp.2021.22010024
Francis J McMahon 1
Affiliation  

The rapid progress in psychiatric genetics over the past 10 years, while exciting from a research perspective, has not yet had an impact on clinical practice. How will we really be able to put genetics to work in the psychiatric clinic? This overview will attempt to answer this question. A survey of widely used methods and major study designs highlights key findings that have emerged so far. These findings inform a broad conceptual model of how genetic risk may act to influence dimensions of psychopathology and clinical presentations. The overview concludes with highlights of some of the most clinically relevant findings to date and their implications for psychiatric practice in the near future.



中文翻译:

将遗传学应用于精神病学诊所

过去 10 年精神遗传学的快速发展虽然从研究的角度来看令人兴奋,但尚未对临床实践产生影响。我们如何才能真正将遗传学应用于精神病诊所?本概述将尝试回答这个问题。对广泛使用的方法和主要研究设计的调查突出了迄今为止出现的主要发现。这些发现为遗传风险如何影响精神病理学和临床表现的维度提供了一个广泛的概念模型。概述总结了迄今为止一些最临床相关的发现及其在不久的将来对精神病学实践的影响。

更新日期:2022-03-03
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