当前位置: X-MOL 学术Sep. Purif. Rev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Separation of Amino Acids and Peptides with Supercritical Fluids Chromatography
Separation and Purification Reviews ( IF 5.4 ) Pub Date : 2022-03-02 , DOI: 10.1080/15422119.2022.2038625
Kaja Kupnik 1, 2 , Željko Knez 1, 3 , Mateja Primožič 1 , Maja Leitgeb 1, 3
Affiliation  

ABSTRACT

This review article provides an overview of supercritical fluid chromatography (SFC) techniques for the separation of amino acids and peptides and modifications of mobile phases in SFC for the separation of highly polar and hydrophilic compounds. Furthermore, it covers SFC applications for the chiral and achiral separations of amino acids and peptides. In this review, detailed explanations of possible and already performed achiral and chiral separations by individual amino acids and peptides are presented. Different stationary phases, separation conditions such as backpressure and temperature, and compositions of the mobile phase with possible additives for each amino acid and peptide are summarized.



中文翻译:

用超临界流体色谱法分离氨基酸和多肽

摘要

这篇综述文章概述了用于氨基酸和肽分离的超临界流体色谱 (SFC) 技术以及用于分离高极性和亲水性化合物的 SFC 中流动相的改进。此外,它还涵盖了用于氨基酸和肽的手性和非手性分离的 SFC 应用。在这篇综述中,详细解释了可能的和已经进行的单个氨基酸和肽的非手性和手性分离。总结了每种氨基酸和肽的不同固定相、分离条件(例如背压和温度)以及流动相的组成以及可能的添加剂。

更新日期:2022-03-02
down
wechat
bug