Little is known about antipsychotic prescription patterns among children and adolescents in Japan, particularly in outpatient settings. We investigated the prevalence and trends of antipsychotic prescription for outpatients aged ≤ 17 years receiving a first antipsychotic prescription from 2006 to 2012 based on a large-scale dispensation dataset. Measurements included age, sex, department of diagnosis and treatment, type of prescription (monotherapy or polytherapy), antipsychotic dosage, and concomitant psychotropic drugs. Of the 10,511 patients, 65.1% were aged 13–17 years, and 52.9% were males. Second-generation antipsychotic monotherapy prescriptions increased from 53.8% in 2006 to 78.3% in 2012. Risperidone was the most frequently prescribed antipsychotic, followed by aripiprazole and olanzapine. Approximately 25.0% of patients were prescribed an initial dose less than recommended. Second-generation antipsychotic monotherapy is currently the most frequent prescription pattern among outpatients aged ≤ 17 years receiving an initial antipsychotic prescription.

关于日本儿童和青少年的抗精神病药物处方模式知之甚少，尤其是在门诊环境中。我们基于大规模配药数据集调查了 2006 年至 2012 年接受第一个抗精神病药处方的 17 岁以下门诊患者的抗精神病药处方流行率和趋势。测量包括年龄、性别、诊断和治疗部门、处方类型（单药或多药）、抗精神病药剂量和伴随的精神药物。在 10,511 名患者中，65.1% 的患者年龄在 13-17 岁之间，52.9% 为男性。第二代抗精神病药单药处方从 ​​2006 年的 53.8% 增加到 2012 年的 78.3%。利培酮是最常用的抗精神病药，其次是阿立哌唑和奥氮平。大约 25 个。0% 的患者的初始剂量低于推荐剂量。第二代抗精神病药单药治疗是目前接受初始抗精神病药处方的 17 岁以下门诊患者中最常见的处方模式。