You spent years investigating your beloved protein. You generated mouse models, found a phenotype and fixed it with a drug. You even used human cells to reveal a conserved mechanism. But a prestigious journal has rejected your manuscript because you did not include females. Here is why you should not be mad at them. Irene Miguel-Aliaga comments on the importance of considering biological sex as an experimental variable.

中文翻译：

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我们来谈谈（生物）性别

您花了数年时间研究您心爱的蛋白质。您生成了小鼠模型，发现了表型并用药物修复了它。您甚至利用人类细胞揭示了一种保守的机制。但一家著名期刊拒绝了你的手稿，因为你没有包括女性。这就是为什么你不应该对他们生气。艾琳·米格尔·阿利亚加 (Irene Miguel-Aliaga) 评论了将生物性别视为实验变量的重要性。