It is every biochemist's dream to reconstitute a biological process in vitro using defined components, because doing so not only reduces a biological phenomenon to one or a series of biochemical reactions, but also defines the minimal list of essential components. In this issue of Genes & Development, Boreikaite and colleagues (pp. 210–224) and Schmidt and colleagues (pp. 195–209) report their independent reconstitution of human pre-mRNA 3′ end processing.

中文翻译：

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人类前体 mRNA 3' 末端加工：重建就是相信

每个生物化学家都梦想使用确定的成分在体外重建生物过程，因为这样做不仅可以将生物现象简化为一个或一系列生化反应，而且还可以定义基本成分的最小列表。在本期Genes & Development中，Boreikaite 及其同事（第 210-224 页）和 Schmidt 及其同事（第 195-209 页）报告了他们对人类前体 mRNA 3' 末端加工的独立重建。