Background Survival from out-of-hospital cardiac arrest (OHCA) is higher if the arrest is witnessed and occurs during exercise, however, there is contradicting data on prognosis with regards to sex and age. The purpose of this study was to compare the outcomes and circumstances of exercise-related OHCA in different age groups and between sexes in a large unselected population. Methods Data from exercise-related OHCAs reported to the Swedish Registry of Cardiopulmonary Resuscitation from 2011 to 2014 and from 2016 to 2018 were analysed. All cases of exercise-related OHCA in which emergency medical services attempted resuscitation were included. The primary outcome was survival to 30 days. Results In total, 635 cases of exercise-related OHCA outside of the home were identified. The overall 30-day survival rate was 44.5% with highest survival rate in the age group 0–35 years, compared with 36–65 years and >65 years (59.6% vs 46.0% and 40.4%, p=0.01). A subgroup analysis of 0–25 years showed a survival rate of 68.8%. Exercise-related OHCA in females (9.1% of total) were witnessed to a lower extent (66.7% vs 79.6%, p=0.03) and median time to cardiopulmonary resuscitation (CPR) was longer (2.0 vs 1.0 min, p=0.001) than in males. Females also had lower rates of ventricular fibrillation (43.4% vs 64.7%, p=0.003) and a lower 30-day survival rate (29.3% vs 46.0%, p=0.02). Conclusion In exercise-related OHCA, younger victims have a higher survival rate. Exercise-related OHCA in females was rare, however, survival rates were lower compared with males and partly explained by a lower proportion of witnessed events, longer time to CPR and lower frequency of a shockable rhythm. All data relevant to the study are included in the article or uploaded as online supplemental information. Not applicable.

中文翻译：

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男性和年轻人因运动相关的院外心脏骤停获得更好的结果：瑞典心肺复苏登记处的研究结果

背景 如果在运动期间目睹并发生心脏骤停，则院外心脏骤停 (OHCA) 的存活率更高，但是，关于性别和年龄的预后数据存在矛盾。本研究的目的是在大量未经选择的人群中比较不同年龄组和性别之间运动相关 OHCA 的结果和情况。方法对 2011 年至 2014 年和 2016 年至 2018 年向瑞典心肺复苏登记处报告的运动相关 OHCA 的数据进行分析。包括所有紧急医疗服务尝试复苏的与运动相关的 OHCA 病例。主要结果是生存至 30 天。结果 总共确定了 635 例在家外与运动相关的 OHCA。总的 30 天生存率为 44。5% 在 0-35 岁年龄组中存活率最高，而 36-65 岁和 >65 岁（59.6% vs 46.0% 和 40.4%，p=0.01）。0-25 岁的亚组分析显示生存率为 68.8%。女性（占总数的 9.1%）发生运动相关的 OHCA 的程度较低（66.7% 对 79.6%，p=0.03），心肺复苏（CPR）的中位时间更长（2.0 对 1.0 分钟，p=0.001）比男性。女性的心室颤动发生率也较低（43.4% 对 64.7%，p=0.003）和 30 天存活率较低（29.3% 对 46.0%，p=0.02）。结论 在与运动相关的 OHCA 中，年轻患者的存活率较高。女性中与运动相关的 OHCA 很少见，但与男性相比，存活率较低，部分原因是目击事件的比例较低，心肺复苏的时间更长，可电击心律的频率更低。所有与研究相关的数据都包含在文章中或作为在线补充信息上传。不适用。