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Depression symptom clusters in adolescents: A latent class analysis in a clinical sample
Psychotherapy Research ( IF 4.117 ) Pub Date : 2022-02-03 , DOI: 10.1080/10503307.2022.2030498
Maria E Loades 1 , Michelle C St Clair 1 , Faith Orchard 2 , Ian Goodyer 3 , Shirley Reynolds 4 , 3
Affiliation  

Abstract

Background

Major depression is clinically heterogeneous. We aimed to identify classes of depressed adolescents with different symptom presentations and examine if these were differentially associated with illness severity, functioning, engagement with treatment, and clinical outcomes.

Method

Baseline depression symptoms of 454 depressed adolescents (age 11–17) from the IMPACT trial were subjected to latent class analysis. We compared classes on self-reported symptoms and social impairment at baseline and follow-up and their engagement in treatment.

Results

We identified three classes of participants which differed in the number and pattern of depression symptoms; Class 1—Severe- (37.2%)—endorsed almost all symptoms and were most functionally impaired; Class 2—Moderate- (41.9%)—endorsed fewer symptoms with high suicidal ideation, self-harm, and worthlessness; Class 3—Somatic (20.9%)—endorsed fewest symptoms, with high somatic symptoms. Groups did not differ on engagement, therapeutic alliance, or post-treatment symptom reduction. Adolescents in the severe and moderate subgroups reported symptom reductions after treatment ended, whilst those in the somatic subgroup did not.

Conclusions

At presentation, high somatic features in depressed adolescents, rather than severity, or impairment levels, may indicate lower liability for responding to psychological treatment.



中文翻译:

青少年抑郁症状群:临床样本中的潜在类别分析

摘要

背景

重度抑郁症在临床上具有异质性。我们旨在确定具有不同症状表现的抑郁青少年类别,并检查这些症状是否与疾病严重程度、功能、参与治疗和临床结果存在差异。

方法

对来自 IMPACT 试验的 454 名抑郁青少年(11-17 岁)的基线抑郁症状进行潜在类别分析。我们比较了基线和随访时自我报告的症状和社会障碍的班级以及他们对治疗的参与。

结果

我们确定了三类在抑郁症状的数量和模式上不同的参与者;1 级——重度——(37.2%)——几乎所有症状都得到认可,功能受损最严重;2 级——中度——(41.9%)——认为具有高度自杀意念、自残和无价值的症状较少;3 级——躯体(20.9%)——认可最少的症状,但躯体症状高。各组在参与、治疗联盟或治疗后症状减轻方面没有差异。重度和中度亚组的青少年报告治疗结束后症状减轻,而躯体亚组的青少年则没有。

结论

在呈现时,抑郁青少年的高躯体特征,而不是严重程度或损伤水平,可能表明对心理治疗的反应责任较低。

更新日期:2022-02-03
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