Regulation of intercellular small RNA (sRNA)-mediated gene silencing in plants is commonly ascribed to hypothetical mechanisms involving movement channels. In this commentary, I present a complementary, perhaps counter-intuitive view, in which sRNA movement is also crucially regulated by the cell-autonomous silencing machinery found in silencing-emitting, traversed and recipient cells. Olivier Voinnet proposes that movement of gene-silencing small RNAs (sRNAs) in plants can be regulated by intracellular sRNA biogenesis and activity factors expressed in silencing-signal emitting, traversed and recipient cells.

中文翻译：

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重新审视植物中的小 RNA 运动

植物中细胞间小 RNA (sRNA) 介导的基因沉默的调节通常归因于涉及运动通道的假设机制。在这篇评论中，我提出了一个互补的、也许是反直觉的观点，其中 sRNA 运动也受到细胞自主沉默机制的关键调节，这些机制存在于沉默发射细胞、穿越细胞和受体细胞中。Olivier Voinnet 提出植物中基因沉默小 RNA (sRNA) 的运动可以通过细胞内 sRNA 生物发生和在沉默信号发射、穿越和受体细胞中表达的活性因子进行调节。