Journal of Developmental & Behavioral Pediatrics ( IF 2.4 ) Pub Date : 2022-08-01 , DOI: 10.1097/dbp.0000000000001061 Peter Jacoby 1 , Andrew Whitehouse 1 , Helen Leonard 1 , Jacinta Saldaris 1 , Scott Demarest 2 , Tim Benke 2 , Jenny Downs 1, 3
Objective:
The aim of this study was to devise an evidence-based missing data rule for the Quality of Life Inventory-Disability (QI-Disability) questionnaire specifying how many missing items are permissible for domain and total scores to be calculated using simple imputation. We sought a straightforward rule that can be used in both research and clinical monitoring settings.
Method:
A simulation study was conducted involving random selection of missing items from a complete data set of questionnaire responses. This comprised 520 children with intellectual disability from 5 diagnostic groups. We applied a simple imputation scheme, and the simulated distribution of errors induced by imputation was compared with the previously estimated standard error of measurement (SEM) for each domain.
Results:
Using a stringent criterion, which requires that the 95th percentile of absolute error be less than the SEM, 1 missing item should be permitted for 2 of the 6 QI-Disability subdomain scores to be calculated and 1 missing item per domain for the total score to be calculated. Other, less stringent criteria would allow up to 2 missing items per domain.
Conclusion:
Empirical evidence about the impact of imputing missing questionnaire responses can be gathered using simulation methods applied to a complete data set. We recommend that such evidence be used in devising a rule that specifies how many items can be imputed for a valid score to be calculated.
中文翻译:
为生活质量问卷设计缺失数据规则——模拟研究
客观的:
本研究的目的是为生活质量量表-残疾(QI-残疾)问卷设计一个基于证据的缺失数据规则,指定使用简单插补计算的领域和总分允许有多少缺失项目。我们寻求一种可用于研究和临床监测环境的简单规则。
方法:
进行了一项模拟研究,涉及从完整的问卷调查数据集中随机选择缺失的项目。这包括来自 5 个诊断组的 520 名智力障碍儿童。我们应用了一种简单的插补方案,并将插补引起的误差的模拟分布与之前估计的每个域的测量标准误差 (SEM) 进行了比较。
结果:
使用严格的标准,要求绝对误差的第 95 个百分位小于 SEM,计算 6 个 QI 残疾子域分数中的 2 个时,应允许缺少 1 个项目,并且每个域的总分数应允许缺少 1 个项目。被计算。其他不太严格的标准允许每个域最多缺失 2 个项目。
结论:
可以使用应用于完整数据集的模拟方法来收集有关估算缺失问卷答复的影响的经验证据。我们建议使用此类证据来设计规则,指定可以估算多少项目才能计算出有效分数。