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Continuous Glucose Monitoring Initiation Within First Year of Type 1 Diabetes Diagnosis Is Associated With Improved Glycemic Outcomes: 7-Year Follow-Up Study
Diabetes Care ( IF 16.2 ) Pub Date : 2022-01-12 , DOI: 10.2337/dc21-2004
Anagha Champakanath , Halis Kaan Akturk , G. Todd Alonso , Janet K. Snell-Bergeon , Viral N. Shah

OBJECTIVE To evaluate long-term glycemic outcomes of continuous glucose monitoring (CGM) initiation within the first year of type 1 diabetes diagnosis. RESEARCH DESIGN AND METHODS Patients with type 1 diabetes (N = 396) were divided into three groups: 1) CGM (CGM use within 1 year of diabetes diagnosis and continued through the study), 2) no-CGM (no CGM use throughout the study), and 3) new-CGM (CGM use after 3 years since diabetes diagnosis). Patients were followed up to 7 years. RESULTS A1c was significantly lower in the CGM compared with the no-CGM group throughout 7 years of follow-up (least squares mean A1c values: 6 months, 7.3% vs. 8.1%; 1 year, 7.4% vs. 8.6%; 2 years, 7.7% vs. 9.1%; 3 years, 7.6% vs. 9.3%; 4 years, 7.4% vs. 9.6%; 5 years, 7.6% vs. 9.7%; 6 years, 7.5% vs. 10.0%; and 7 years, 7.6% vs. 9.8%; for all, P < 0.001) adjusting for age at diagnosis, sex, and insulin delivery method. CONCLUSIONS CGM initiation within first year of type 1 diabetes diagnosis results in long-term improvement in A1c.

中文翻译:

在 1 型糖尿病诊断的第一年内启动持续血糖监测与改善血糖结果相关:7 年随访研究

目的 评估在诊断 1 型糖尿病的第一年内开始连续血糖监测 (CGM) 的长期血糖结果。研究设研究)和 3)新 CGM(糖尿病诊断后 3 年后使用 CGM)。患者随访长达 7 年。结果 在 7 年的随访中,CGM 组的 A1c 显着低于非 CGM 组(最小二乘平均 A1c 值:6 个月,7.3% 对 8.1%;1 年,7.4% 对 8.6%;2年,7.7% 对 9.1%;3 年,7.6% 对 9.3%;4 年,7.4% 对 9.6%;5 年,7.6% 对 9.7%;6 年,7.5% 对 10.0%;和7 年,7.6% 对 9.8%;对于所有情况,P < 0。001) 调整诊断时的年龄、性别和胰岛素输送方法。结论 在诊断 1 型糖尿病的第一年内开始 CGM 会导致 A1c 的长期改善。
更新日期:2022-01-12
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