Objective. The objective of the current study was to analyze the research hotspot of drug treatment for tuberculosis via top literatures. Materials and Methods. A retrospective analysis was performed on June 7th, 2021. Literatures were searched on the Web of Science Core Collection to identify the top 50 cited literatures related to drug treatment of tuberculosis. The characteristics of the literatures were identified. The outcomes included authorship, journal, study type, year of publication, and institution. Cooccurrence network analysis and visualization were conducted using the VOS viewer (Version 1.6.16; Leiden University, Leiden, The Netherlands). Results. The top 50 cited literatures were cited 308 to 2689 times and were published between 1982 and 2014. The most studied drugs were the first-line drugs such as isoniazid and rifampicin (), and drug-resistant tuberculosis was most frequently reported (). They were published in 18 journals, and the New England Journal of Medicine published the most literatures (), followed by the American Journal of Respiratory and Critical Care Medicine (), and the Lancet (). The authors were from 13 countries, and the authors from the USA published most of the literatures (), while authors from other countries published less than five literatures. The CDC in the USA (), the World Health Organization (WHO) (), and the American Philosophical Society () were the leading institutions, and only two authors published at least two top-cited literatures as first authors. Conclusions. This study provides insights into the development and most important literatures on drug therapy for tuberculosis and evidence for future research on tuberculosis treatment.

中文翻译：

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结核病药物治疗研究热点分析——基于前50篇被引文献的文献计量学

客观的。本研究旨在通过顶级文献分析结核病药物治疗的研究热点。材料和方法。于 2021 年 6 月 7 日进行了回顾性分析。在 Web of Science 核心合集中检索文献，确定与结核病药物治疗相关的前 50 篇被引文献。确定了文献的特征。结果包括作者身份、期刊、研究类型、出版年份和机构。使用 VOS 查看器（版本 1.6.16；莱顿大学，莱顿，荷兰）进行共现网络分析和可视化。结果。1982年至2014年间发表的前50篇被引文献被引用308～2689次。研究最多的药物是异烟肼、利福平等一线药物。)，耐药结核病的报道最多（）。它们在 18 种期刊上发表，其中《新英格兰医学杂志》发表的文献最多（），其次是美国呼吸与重症监护医学杂志（)和柳叶刀(）。作者来自13个国家，其中美国作者发表了大部分文献（)，而其他国家的作者发表的文献少于五篇。美国疾控中心（),世界卫生组织 (WHO) ()和美国哲学学会 ()是领先的机构，只有两位作者作为第一作者发表了至少两篇高被引文献。结论。本研究为结核病药物治疗的发展和最重要的文献提供了见解，并为结核病治疗的未来研究提供了证据。