In the sixth edition of the World Health Organization manual for the examination and processing of human semen, extended examination methods to provide key diagnostics in the investigation of the male reproductive system function are elaborated. These go beyond the basic analysis of semen and may be useful in more specifically guiding the clinical characterization of fertile or infertile men. Among the extended examinations included in the chapter, the use of multiparametric scoring for sperm morphological defects, sperm DNA fragmentation, and the roles for computer-assisted analysis of sperm or semen are arguably those that will be the most widely used and may also cause the most debate.

在世界卫生组织人类精液检查和处理手册第六版中，详细阐述了为男性生殖系统功能调查提供关键诊断的扩展检查方法。这些超越了精液的基本分析，可能有助于更具体地指导有生育能力或不育男性的临床特征。在本章包含的扩展检查中，多参数评分对精子形态缺陷、精子 DNA 片段化的使用以及对精子或精液进行计算机辅助分析的作用可以说是应用最广泛的那些，也可能导致大多数辩论。