Importance: Previous reports have suggested reductions in mortality risk from COVID-19 throughout the first wave of the COVID-19 pandemic. Mortality changes later in the pandemic and pandemic effects on other types of geriatric hospitalizations are less studied. Objectives: To describe the changes in hospitalizations and 30-day mortality in Stockholm for patients 70+ receiving inpatient geriatric care for COVID-19 and other causes. Design: Observational study. For patients 70 or older, we present the incidence of 30-day mortality from COVID-19 in the Stockholm region, in relationship to geriatric hospitalizations and 30-day mortality after admission for COVID-19 and other causes. Setting: Hospitalizations for patients 70+ from geriatric clinics in Stockholm, Sweden hospitalized for COVID-19 or other causes between March 2020 and July 31, 2021, were included. Participants: The total number of geriatric hospitalizations for patients 70+ was 5,320 for COVID-19 and 32,243 for non-COVID-19 causes, corresponding to 4,565 individual COVID-19 patients and 19,308 non-COVID-19 patients. Exposure(s): The date of hospital admission to a geriatric clinic. Main Outcome(s) and Measure(s): 30-day mortality after admission. Results: In patients with COVID-19, the 30-day mortality rate was highest at the beginning of the first wave (29% in March-April 2020), decreased as the first wave subsided (7% July-August), increased again in the second wave (17% November-December), but failed to increase as much in the third wave (11-13% March-July 2021). In non-COVID-19 geriatric patients during the same period, the 30-day mortality presented a similar trend, but with a smaller magnitude of variation (5 to 10%). The number of persons 70 or older testing positive for COVID-19 in Stockholm reached two peaks in 2020 (April and December), fell in January 2021 and then increased again in March-April 2021. Conclusions and Relevance: During the first and second waves, hospital admissions and 30-day mortality after geriatric hospitalization for COVID-19 increased in periods of high community transmission, although the mortality peak was lower in wave 2 than in wave 1. The mortality for non-COVID geriatric cases was lower and more stable but also showed an increase with the pandemic peaks.

中文翻译：

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2020 年 3 月至 2021 年 7 月 COVID 大流行期间老年患者​​住院和 30 天死亡率的时间趋势

重要性：之前的报告表明，在第一波 COVID-19 大流行期间，COVID-19 的死亡风险有所降低。大流行后期的死亡率变化以及大流行对其他类型的老年住院治疗的影响研究较少。目标：描述斯德哥尔摩因 COVID-19 和其他原因接受老年病住院治疗的 70 岁以上患者的住院率和 30 天死亡率的变化。设计：观察性研究。对于 70 岁或以上的患者，我们展示了斯德哥尔摩地区因 COVID-19 导致的 30 天死亡率与老年人住院率和因 COVID-19 和其他原因入院后 30 天死亡率的关系。设置：2020 年 3 月至 2021 年 7 月 31 日期间，瑞典斯德哥尔摩老年诊所因 COVID-19 或其他原因住院的 70 岁以上患者的住院情况，被包括在内。参与者：70 岁以上患者的老年住院总人数为 COVID-19 5,320 人和非 COVID-19 原因 32,243 人，对应于 4,565 名 COVID-19 患者和 19,308 名非 COVID-19 患者。暴露（S）：入院到老年诊所的日期。主要结果和测量：入院后 30 天死亡率。结果：在 COVID-19 患者中，第一波开始时的 30 天死亡率最高（2020 年 3 月至 4 月为 29%），随着第一波消退而下降（7 月至 8 月为 7%），再次上升在第二波（11 月至 12 月为 17%）中，但在第三波（2021 年 3 月至 7 月为 11-13%）中未能增加那么多。在同一时期的非 COVID-19 老年患者中，30 天死亡率呈现类似趋势，但变化幅度较小（5% 至 10%）。