Figen Öngöz Dede¹; Cankat Kara¹; Ceren Gökmenoğlu¹; Varol Çanakçı¹; Doğu Ömür Dede²; Kübra Çelen³; İpek Turan^1,*

¹Periodontology; ²Prosthodontics, Ordu University, Faculty of Dentistry; ³Oral and Dental Health Center, Ordu, Turkey

Background: Autogenous soft tissue graft (ASTG) contributes to mid-facial soft tissue stability following both periodontal and peri-implant plastic surgical reconstruction. The wound at the palatal donor site where the ASTGs are harvested is frequently associated with patient discomfort.

Aim/Hypothesis: The aim of the study was to evaluate the effects of advanced-platelet rich fibrin (A-PRF) and concentrated growth factor (CGF) on palatal wound healing after ASTG harvest.

Material and Methods: A total of 24 patients were randomized after ASTG; Group 1 (n = 8): A-PRF membrane, Group 2 (n = 8): CGF membrane, and Group 3 (n = 8): sterile wet gauze compression were placed over the palatal wounds. Patients were assessed at 1, 2, 3, and 4 weeks after surgery for bleeding, postoperative discomfort, re-epithelialization, sensation scores, changes in feeding habits and the consumption of analgesics.

Results: Statistically significant improvements were found for all parameters in the Groups 1 and 2 compared with Group 3 (p < 0.001), but there was no significant difference between groups 1 and 2 (p > 0.05).

Conclusion and Clinical implications: The A-PRF and CGF palatal bandage may significantly benefit palatal wound healing and decrease the patients’ morbidity.

Disclosure of Interest: F. Öngöz Dede Conflict with: Ordu University, Faculty of Dentistry, Altınordu, C. Kara: None Declared, C. Gökmenoğlu: None Declared, V. Çanakçı: None Declared, D. Ö. Dede: None Declared, K. Çelen: None Declared, I. Turan: None Declared.

Keywords: biocompatibility, clinical studies/trials, patient satisfaction

Figen Öngöz Dede ¹ ; 坎卡特卡拉¹ ; Ceren Gökmenoğlu ¹ ; 瓦罗尔恰纳克奇¹ ; Doğu Ömür Dede ² ; 库布拉切伦³ ; 伊佩克图兰^1,*

¹牙周病学；²口腔修复学，奥尔杜大学，牙科学院；³口腔和牙科健康中心，土耳其奥尔杜

背景：自体软组织移植物 (ASTG) 有助于牙周和种植体周围整形外科重建后的中面部软组织稳定性。采集 ASTG 的上颚供体部位的伤口经常与患者不适有关。

目的/假设：该研究的目的是评估晚期富含血小板的纤维蛋白 (A-PRF) 和浓缩生长因子 (CGF) 对 ASTG 收获后腭部伤口愈合的影响。

材料和方法：共有 24 名患者在 ASTG 后随机分组；第 1 组（n = 8）：A-PRF 膜，第 2 组（n = 8）：CGF 膜，第 3 组（n = 8）：将无菌湿纱布加压置于上颚伤口上。在术后 1、2、3 和 4 周评估患者的出血、术后不适、上皮再形成、感觉评分、饮食习惯的变化和镇痛剂的消耗。

结果：与第 3 组相比，第 1 组和第 2 组的所有参数均有统计学显着改善（p < 0.001），但第1 组和第 2 组之间没有显着差异（p > 0.05）。

结论及临床意义： A-PRF和CGF腭部绷带可显着促进腭部创面愈合，降低患者的发病率。

利益披露：F. Öngöz Dede 与：Ordu 大学、Altınordu 牙科学院、C. Kara：未声明、C. Gökmenoğlu：未声明、V. Çanakçı：未声明、D. Ö. Dede：未声明，K. Çelen：未声明，I. Turan：未声明。

关键词：生物相容性，临床研究/试验，患者满意度