Summary: 

The use of antibiotic-impregnated cement as a local antibiotic delivery system is well-established as an adjunctive treatment for chronic osteomyelitis. Because the elution of antibiotics is a surface area phenomenon, the geometry of the cement is an important consideration. The antibiotic cement bead rouleaux technique is a simple and efficient method of bead fabrication that requires only 10 minutes of preparation time and readily available operating room supplies. The discoid structure of the beads provides 3 times the surface-area-to-volume ratio of a spherical bead, which facilitates antibiotic elution. Given the speed and ease of fabrication, along with optimized geometry, the antibiotic cement bead rouleaux is a useful addition to the surgeon's repertoire.

中文翻译：

---

抗生素水泥珠 Rouleaux：最大化水泥珠表面积与体积比以改善抗生素洗脱的技术技巧

概括： 

使用抗生素浸渍水泥作为局部抗生素输送系统已被广泛用作慢性骨髓炎的辅助治疗。因为抗生素的洗脱是一种表面积现象，所以水泥的几何形状是一个重要的考虑因素。抗生素水泥珠轮盘技术是一种简单有效的珠子制造方法，只需 10 分钟的准备时间和现成的手术室用品。珠子的盘状结构提供了 3 倍于球形珠子的表面积与体积比，这有助于抗生素洗脱。考虑到制造的速度和易用性，以及优化的几何形状，抗生素水泥珠轮盘是外科医生的有用补充。