Regeneration of zwitterionic surfaces is a promising strategy to combat biofouling. In this study, we have prepared degradable hyperbranched anti-biofouling polymers of methyl methacrylate, tertiary carboxybetaine ester (TCB), and divinyl monomers via reversible addition-fragmentation chain transfer (RAFT) polymerization. The degradation rate of such polymers is a function of the content or type of divinyl monomers. As the content of methacrylic anhydride (MAAH) increases, the degradation rate of the polymer becomes faster; whereas, a change of the divinyl monomers causes the degradation rate to follow a descending order: N,N′-adipic bis(diacetone acrylamide hydrazone) (DAA₂H) > MAAH > ethylene glycol dimethacrylate (EGDMA). Antibacterial and anti-diatom assays show that the coatings inhibit the adhesion of the marine bacteria Pseudomonas sp. and the diatom Navicula incerta. The polymeric coating is expected to be applied in marine anti-biofouling.

两性离子表面的再生是对抗生物污垢的一种很有前景的策略。在这项研究中，我们通过可逆加成-断裂链转移 (RAFT) 聚合制备了甲基丙烯酸甲酯、叔羧基甜菜碱酯 (TCB) 和二乙烯基单体的可降解超支化抗生物污垢聚合物。这种聚合物的降解速率是二乙烯基单体的含量或类型的函数。随着甲基丙烯酸酐（MAAH）含量的增加，聚合物的降解速度变快；然而，二乙烯基单体的变化导致降解速率遵循降序：N , N '-己二酸双（双丙酮丙烯酰胺腙）（DAA ₂H) > MAAH > 乙二醇二甲基丙烯酸酯 (EGDMA)。抗菌和抗硅藻试验表明，涂层抑制了海洋细菌假单胞菌的粘附。和硅藻Navicula incerta。该聚合物涂层有望应用于海洋防生物污损。