Herein, we Design and synthesis of a composite material consisting of cobalt oxide anchored on graphene oxide (Co3O4@GO) as an electrode modifier, and their application to the detection of folic acid (FA) has been investigated. The integration of Co3O4 and GO is by hydrothermal assisted synthesis route. The morphology and crystalline structure of the Co3O4@GO has been well analyzed by XRD, XPS, FESEM, HR-TEM, and EDX analysis. The electrochemical test of the Co3O4@GO modified electrode shows an interesting electrochemical performance for the selective determination of FA with a broad concertation range of 0.1-4000 µM and a lower detection limit (LOD) of 0.024 µM. The enhancement in the catalytic activity of Co3O4@GO can be achieved by the synergistic effect of Co3O4and GO, high electron transportation, and unique spherical structure of Co3O4@GO. The newly developed Co3O4@GO sensor also displays excellent sensitivity of 47.23 µAµM−1 cm−2. Finally, this Co3O4@GO sensor is demonstrated for the detection of FA in the human urine sample with excellent recovery.

中文翻译：

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氧化钴纳米粒子修饰的氧化石墨烯对叶酸检测的电催化性能

在此，我们设计和合成了一种由锚定在氧化石墨烯上的氧化钴 (Co3O4@GO) 组成的复合材料作为电极改性剂，并研究了它们在叶酸 (FA) 检测中的应用。Co3O4 和 GO 的整合是通过水热辅助合成路线。Co3O4@GO 的形貌和晶体结构已经通过 XRD、XPS、FESEM、HR-TEM 和 EDX 分析得到了很好的分析。Co3O4@GO 修饰电极的电化学测试显示出一种有趣的电化学性能，用于选择性测定 FA，具有 0.1-4000 µM 的广泛协调范围和 0.024 µM 的检测下限 (LOD)。Co3O4@GO催化活性的增强可以通过Co3O4和GO的协同作用、高电子传输以及Co3O4@GO独特的球形结构来实现。新开发的 Co3O4@GO 传感器还显示出 47.23 µAµM-1 cm-2 的出色灵敏度。最后，该 Co3O4@GO 传感器被证明可用于检测人尿样品中的 FA，并具有良好的回收率。