plasma and platelets in some ratio relative to the red cells, such as the “1:1:1” combination of 1 units of red cells, 1 unit of plasma, and 1 donor’s worth of pooled platelets. Empiric transfusion increases the rate of overtransfusion when unnecessary blood products are administered based on a formula and not on at patient’s hemostatic profile. Viscoelastic hemostatic assays (VHAs) are point-of-care hemostatic assays that provided detailed information about abnormal clotting pathways. VHAs are used at many centers to better target hemostatic therapies in trauma. This Pro/Con section will address whether VHA guidance should replace empiric fixed ratio protocols in major trauma....

中文翻译：

---

赞成与反对的辩论：粘弹性止血试验应取代固定比例的创伤中大量输血方案

血浆和血小板与红细胞呈某种比例，例如 1 个单位的红细胞、1 个单位的血浆和 1 个供体的汇集血小板的“1:1:1”组合。当根据公式而不是根据患者的止血情况给予不必要的血液制品时，经验性输血会增加过度输血的发生率。粘弹性止血试验 (VHA) 是即时止血试验，可提供有关异常凝血途径的详细信息。许多中心使用 VHA 来更好地针对创伤止血疗法。本赞成/反对部分将讨论 VHA 指南是否应取代重大创伤中的经验性固定比率协议……