Gas hydrates formation is a major challenge to effective hydrocarbons flow in pipelines; thus, flow assurance is a remedy. The use of gas hydrate inhibitors is commonly used as an effective method to inhibit gas hydrate formation. This study focuses on the toxicological issues of conventional gas hydrate inhibitors. The study evidence reveals that conventional chemical additives that ensure effective flow assurance are said to contribute significantly to environmental change and damage. This is attributed to their toxicity nature that poses a great environmental risk by such chemical inhibitors; more so thermodynamic inhibitors due to their dissociation ability that affects seafloor stability. This leads to the release of methane (and associated gases) and other toxic components into the column water. However, little is known about the actual toxicity of frequently used gas hydrate inhibitors. This calls for an in-depth study into such and also the development of greener inhibitors to replace the existing ones.

中文翻译：

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常规气体水合物抑制剂的毒理学问题

天然气水合物的形成是油气在管道中有效流动的主要挑战；因此，流量保证是一种补救措施。气体水合物抑制剂的使用通常被用作抑制气体水合物形成的有效方法。本研究侧重于常规气体水合物抑制剂的毒理学问题。研究证据表明，确保有效流动保证的传统化学添加剂据说对环境变化和破坏有重大贡献。这归因于它们的毒性性质，这种化学抑制剂对环境构成了巨大的风险；热力学抑制剂更是如此，因为它们的解离能力会影响海底稳定性。这导致甲烷（和相关气体）和其他有毒成分释放到塔水中。然而，人们对常用的天然气水合物抑制剂的实际毒性知之甚少。这需要深入研究这种情况以及开发更环保的抑制剂来替代现有的抑制剂。